Low Histamine Probiotics--Can Probiotics Be BAD for You?

Is it possible that your probiotic could be making you sick?  Sadly, it is! In this post about low-histamine probiotics I'll share what histamine is and what that has to do with probiotics, and why your probiotics might not be doing you any favors.

Probiotics are something that's commonly accepted as being good for everyone. Gut health is crucial for overall health and probiotics are beneficial bacteria that help to recolonize the gut to restore balance.  So one would think that taking probiotics is always a good thing.  Right?

Wrong.

bottle of probiotics with healthy foods in front - low histamine probiotics

For some people, taking probiotics could be a completely bad idea.

That is, if they are taking the wrong kind of probiotic.

Histamine intolerance is something that we've talked about on the blog before.  In this post we talked about what histamine intolerance is and in this post we talked about how to deal with a histamine intolerance, or histamine allergy.

One thing that wasn't mentioned, however, is the role that probiotics play in histamine intolerance treatment.

Yikes--Could I Have Histamine Intolerance?

Around Christmas of this past year, I kind of "fell into" a detox.   Just in case you were wondering, detox isn't the best idea during the Holiday Season--I don't recommend it. However, the whole thing led to some very interesting information which I will now pass on to you.

It all started with my taking a heavy-duty liquid fermented superfood probiotic.  I'd taken it years ago and it had clearly done some heavy duty work on my gut.  This time, however, I felt I needed to get out of my current probiotic rut and give that product another go.  It went well for awhile, but then the reactions got a little intense. They subsided, but then resurfaced elsewhere, and I was pretty scared that I was histamine intolerant.

So I plunged into researching histamine intolerance online and was determined to figure out what I could do about it.

One of the recommendations that I found was to get on a low histamine probiotic so as to recolonize the gut without inflaming the already problematic condition.

What Is Histamine?

We covered quite a bit about histamine in this post, but here's a quick review.

Histamine is a chemical produced by your body that is involved in your immune system, proper digestion, and central nervous system during immune responses.  It sends messages from your body to your brain, and is a component of stomach acid (which helps you digest your food -- I've talked about stomach acid and rosacea before).  But the role of histamine that is central to our discussion today is how histamine is involved with the immune system.

You mostly like are familiar with the word "histamine" as it being a part of the word "anti-histamine" -- those substances that one takes when allergies are being a bother. Histamines are alerting your body of a real (or mistaken) offender and cause an inflammatory response.  And it causes this all over the body.

If your body can't break down the histamine well or fast enough, you end up with histamine intolerance.

That leads to the problems outlined in this post on histamine intolerance, but basically you can have all kinds of symptoms including things that one would typically associate with allergies, such as:

bottle of probiotics with healthy foods in front - low histamine probiotics

Histamine and Probiotics

Basically, if you have a histamine intolerance issue, the last thing that you want is to be taking probiotics that make more histamine.  If you do that, instead of getting healthier, you could be exacerbating an underlying health issue and well--your probiotics could be making you sick.

And if you are making your own Water Kefir, Homemade Sauerkraut, and more, that may or may not be a good idea depending on your issues with histamine.

Additionally, there are some probiotic strains that have been shown to be helpful in reducing the histamine response.

According to the research that I have done, the following are various probiotic strains and the effect that they have on histamine levels.  Of course that research could change in the future.

Histamine Raising Probiotic Strains

  • Lactobacillus bulgaricus
  • Lactobacillus casei
  • S. thermophilus
  • Lactobacillus delbrueckii
  • B Lichenformis - appears to raise histamine (source)
  • Lactobacillus helveticus

Histamine Lowering Strains

  • Bifidobacterium infantis
  • Lactobacillus gasseri
  • Lactobacillus rhamnosus
  • Bifidobacterium longum
  • Lactobacillus plantarum
  • Bifidobacterium breve
  • Lactobacillus salivarius
  • Bifidobacterium lactis
  • Bifidobacterium Bifidum - (source)
  • Lactobacillus reuteri**Lactobacillus reuteri is kind of in a class by itself.  Many place it in the "histamine producing" category, but interestingly enough, it doesn't belong there. Lactobacillus reuteri does, in fact, cause histidine to convert to histamine, but this histamine raises cAMP which actually reduces the inflammatory response.  Fascinating!  I therefore put it in the "histamine reducing" class due to this aspect. (3)

Lactobacillus plantarum does not appear to have an effect on histamine but lowers/inhibits tyramine and putrescine.

Histamine Neutral Strains

  • Lactobacillus acidophilus
  • Lactobacillus Lactis
  • Lactococcus Lactis

Bacillus Coagulans

It's possible that other strains might end up have their own special section as well in the future, as more is known about them, but Bacillus Coagulans appears to be a bit unique and I had trouble sorting this strain out.

There is research stating that the B. Coagulans SL5 causes increased histamine, but the B. Coagulans in 2 of the gut health products that I recommend below is MTCC 5856, which is a different strain. In fact, Lactospore (MTCC 5856) is used in some supplements that are made to support those with histamine issues.

Furthermore, there is also this research showing that B. Coagulans is helpful in allergic situations on a number of fronts.

Not Histamine Lowering But....

The following strains aren't typically referred to as being "histamine lowering" strains, but some research shows that they might support the body in ways that would benefit those struggling with histamine intolerance

  • Saccharomyces-Boulardii.
    There are a number of studies on its effectiveness in treating gastroenteritis (source).  Some researchers have linked this condition to high histamine/mast cell issue (source 1 & source 2).  So possibly this strain could be a good support.
    There are some reports apparently about this yeast causing histamine issues in some people, but it has been used for detoxifying gliotoxin (source) and apparently increases DAO production which means it should help with histamine issues. (source)
  • L. Paracasei has been shown to possibly help with leaky gut or allergies (source)
  • L. Casei Shirota
    Although L. Casei has been shown to raise histamines, L. Casei Shirota has been shown to modulate histamine levels. (source)
  • Lactobacillus Crispatus has been shown to have anti-allergenic effects (source)

How to Sort All of This Information Out

Does this all make you feel like your head is going to burst?

I get it.

Basically, if you are looking to avoid probiotic strains that might make histamine issues (and inflammation) worse, you want to avoid the Histamine-Raising Strains and get probiotics that have the Histamine-Lowering Strains in them and if they have the Histamine-Neutral Strains in them that's fine too.

Make sense?

So---In order to work on mine and my son's possible histamine issues, I went a hunt to find probiotics that had the strains that we wanted but didn't have the problematic strains.

It was quite a job, trying to figure out what to buy with all of those "lacto this" and "bifido that" words popping out at me. I thought I would go a little cross-eyed trying to sort it all out, but I did find some products that were just perfect for what I was looking for.

Where to Buy Low-Histamine Probiotics

I buy my supplements in several places.  One of my favorite places to shop is Iherb.  They have fast service and very very good prices.  Another great option is Pure Formulas.

Some of the brands listed below, like Metagenics, claim that their product is fine when not refrigerated during shipping, etc.  If you are concerned about that please take care to buy them either in a store where they are refrigerated or have them shipped in a cold pack.

Following are a bunch of options that will fit the bill......

Low-Histamine Probiotic Single Strains

Following are individual strains of bacteria that should be helpful for histamine intolerance.

Most natural practitioners who recommend rotating between different kinds of probiotics so as to populate the gut with different strains.  So purchasing several or all of the above varieties and rotating between them would achieve that goal.

Low Histamine Probiotic Blends

Personally, I think a blend is a better option than a single strain since you are getting more beneficial "bugs" into your gut. It's like facing the bad guys with a multi-faceted assault instead of a single strategy.

1. Smidge (Formerly GutPro)

Recently, our family started using Smidge (formerly GutPro). It's a probiotic unlike many others in that it's super concentrated. It's not cheap, but it lasts a REALLY REALLY long time.

Just a teensy bit on a teensy spoon is all you need.

I have tried so many probiotics over the years, and with many of them, I feel NOTHING. But with Smidge?  Gurgle gurgle gurgle.....something is happening for sure!

Important: make sure to get the teensy stainless spoons that Organic3 has if you get this product because you are going to need them!

Depending on how you use the probiotics, you might want to order two sets of spoons so if one is dirty you have another set at the ready. You absolutely must not use the spoons for these probiotics if they are damp at all, as that will compromise the bacteria. Wet bacteria, in this case, is dead bacteria.

2. Seeking Health Probiota HistaminX

This blend was created for the express purpose of having a blend for those with histamine intolerance. Some have said that this probiotic blend has really helped with their histamine issues, both with probiotics and to other foods. The company has a great Subscribe and Save program so you can save money. Some people use this product alongside the company's Histamine Block.

3. Amare Quadbiotic Low-Histamine Blend with Weight Loss Benefits

This blend of pre, pro, post, and phytobiotics is also low-histamine with the added benefit of it promoting weight loss.

Amare Global's GBX Fit

It contains:

  1. Orange Peel Extract - known to be anti-histamine (source)
  2. Acacia Gum - know to help create a gut environment that's helpful for those with histamine issues
  3. Lactobacillus plantarum - histamine reducer
  4. Bifidobacterium lactic - histamine reducer

This link, also provided above, gives $10 off.

I notice a clear reduction in bloating and appetite change when using this.

Following are some blends of various strains that should not exacerbate histamine intolerance and might even help heal it.

What probiotics do you use--please share in the comments below?

Sources:

1. https://www.ncbi.nlm.nih.gov/pubmed/18544899

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042653/

3. https://www.ncbi.nlm.nih.gov/pubmed/22384111

4.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316997/

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312 Comments

  1. Hello. Thanks for sharing all this interesting information. I’ve read that Yakult is supposed to be good for allergies. Do you know if it’s low histamine? The strain is L Casei Shirota. I know you said L Casei is high histamine. Thank you.

        1. Hi there. Just check the post and the strain you asked about it in there now w/ information about it. Hope that helps!

          1. Yes, I got the information. Thank you ever so much. The ? I sent was supposed to be an emoji thumbs up but came out differently for some reason. Thanks again.

              1. Hi,
                Thanks for this informative post. I wonder if you have any information regarding the strain lactobacillus crispatus and histamine? I've read it's a very good probiotic strain for women to take as it adheres to the vaginal wall very well. However, I can't find any information if it's safe for histamine sensitivity. Any ideas?

  2. Thank you for this page. Do you know where S. Cremoris, which I believe is Streptococcus cremoris, falls in the scheme of things? (I have mast cell activation disorder.) It is used in cheesemaking. I think all soft cheeses, like cream cheese, soft goat cheese, I'm pretty certain would have it. Can't find info about it relating to mast cells however. Thanks in advance!

    1. You are so welcome! I can't find anything specific--only information about how to make it create more amines. Sorry and thanks for reading!

  3. which probiotics names do u suggest if a person has to take an antibiotic?
    I am prone to thrush, but presently I have a sinus infection for 2 weeks and the dr wants to be take Amoxicillin. I have had thrush in the past after taking medications so I am concerned. I want to take a good probiotic with helpful strains.

    1. Hi there. There are so many to choose from it's hard to know. One thing to note is that most probiotics should be taken 2 hours or more away from antibiotics, but this brand says you can take theirs WITH antibiotics at the same time.

      Here is my affiliate link https://justthrivehealth.com/?rfsn=2955029.720bd

      and you can get 15% off with code wholenewmom.

      You can read more about their usage with antibiotics here. Hope that helps!

  4. Hi, would you happen to know if Saccharomyces Boulardii by SeekingHealth is low in histamine? I've been taking about 4 days now and experiencing a bit of brain fog, sleeping a lot, major bloating. It however almost eradicated the pain from my left shoulder which was injured over 2 years ago. Maybe, there's a parasite in me which is causing the pain in my shoulder. Everything's so confusing.

    1. Hi there! The info for Saccharomyces Boulardii is in the post. I am taking it currently as well. Yes, it's hard to sort everything out!

  5. I'm planning on ordering Bacillus Coagulans MTCC 5856 but before I do, I want to confirm that it is not high in histamine? I'm currently taking D-Lactate and Histamine free probiotic which I'm doing great on but I'm still far from perfect and I figured the MTCC 5856 can help control my diarrhea better

    1. Hi there. According the research that I shared in the post that strain isn't high in histamine. If you search the post for MTCC 5856 you can see the information. Hope that helps!

  6. what abut low-salicylate probiotics? do you have any info about strains and/or brands you recommend for those who are Salicylate sensitive as well?

  7. I use this probiotic listed on another site for low histamine. - Vitanica, Flora Symmetry, Intestinal Probiotic Support, Vegetarian, 60 Count - So far seems good. However, I am on day two of NOW Saccharomyces Boulardii, and I seem to get throat congestion after taking it. Hmmm just pondering if it could be the guar gum in it?

    Thanks!

    1. Hi there--I really don't know but Saccharomyces Boulardii has a variety of actions including acting (according to Neil Nathan, MD) as a binder for mold so I don't know. Have you reacted to guar gum before?

      1. Just adding my 2 cents....
        I am not a fan of guar gum at all!! I'm definitely no expert (and very new to the histamine issue), the reason I went down this road is because I have IBS, which I control with diet. I read recently IBS issues could be caused by histamine reactions. Years ago I took Saccharomyces Boulardii and didn't like it at all. I think it made me more bloated than usual (I didn't finish the very expensive bottle I bought). I just recently realized all the gums they put in as additives to foods, such as ice cream & coconut milk, do a number on me! The worst are Guar Gum, Locust Bean Gum (aka Carob Bean Gum) and Inulin (Chicory Root). They give me horrible, painful bloating & gas. Personally if a supplement had Guar Gum in it, I wouldn't take it. (It's possible that old S.B probiotic I took had it & I just didn't know). I know the original poster didn't mention anything about digestive issues, but I just thought I'd mention my experience with both S.B. & guar gum.

        Due to the possible link between IBS & histamines, I am about to purchase Vitanica, Flora Symmetry, Intestinal Probiotic Support to see how it goes. I am also going to start taking Natural D-Hist....maybe I'll have some luck!

        Thanks so much for posting all this info! It's extremely helpful!!

        1. Super interesting. Sorry you are having all of these issues. I'm a firm believer in going for the root cause and often it's tied to lowering toxicity and improving what you put into your body. Hope this all helps you!

  8. I bought GutPro but it's done nothing for me or my family. My naturopath told me that powdered probiotics aren't very effective. It's also really expensive!

    1. Hi there--that's interesting. What kind of probiotic does your naturopath recommend? There are a lot of people who have great responses to powdered probiotics so not sure what the reasoning would be there. Was there an explanation given as to why powdered isn't recommended?

      1. She recommends a probioitc that releases its bacteria slowly. Apparently powders just get eaten up in the stomach. The one she gave me was much more effective for my digestion.

        1. Hi again - do you mean a capsule? GutPro is apparently proven to not get eaten up in the stomach. I hope to add some more to this list :).

          1. Most capsules can't protect their bacteria in the stomach, so I don't know how a powder could possibly do that? It doesn't give the bacteria any protection at all.

            1. Hello again. Got this answer back from GutPro. Hope this helps!

              GutPro is taken with meals, to raise the PH in the gut for the bacteria to pass and be absorbed. Most probiotics are taken on an empty stomach which may leave it susceptible and not make the transit. GutPro bacteria are very hardy and can withstand lower PH ranges than most think. However, taking it with a meal containing good fats add another layer of protection for the bacteria.

          2. GutPro gave me the runs big time, and didn't seem to reduce histamine issues. I'm going to try Lynch's Probiota HistaminX -- it has lots of good reviews on Amazon (which I know is just anecdotal). At least they gave me a refund.

            But interestingly, it has different proportions of the same bacteria that's in GutPro, but doesn't have the l. gasseri, which another blog says has been shown to produce histamine in certain circumstances.

            One thing that's helped me recently is saccharomyces boulardi.

            1. Hi there. Sorry you had that issue w/ the GutPro- maybe too much too soon? It can be really powerful!

              I just added a link to the Probiota in my post along with some possible good companions for you. I had meant to do that for awhile so thanks for the reminder. They have a money saving option as well.

              About the L Gasseri, could you direct me to where you have seen that?

              I like Saccharomyces Boulardi--using it now for addressing mold toxicity. Neil Nathan uses it in his practice. thanks!

          3. Not sure if this will show up in the right place. I couldn't find a reply tab under your reply Adrienne.

            Anyway, thanks for your speedy reply. I'm not sure if I used 'too much' or not...it's been about 7-8 months, so the brain fog prevents exact recall. I do remember using that scoop, at least at first, so I'm guessing that I started as per their dosing.

            Here's the link -- on Alison Vickery's site. I've seen some conflicting and sometime erroneous info there, but she cites a study to back up the claim, and as you'll see, it also mentions b. longum and salivarius as problem strains, but perhaps only under some circumstances.

            (post appears to be gone so link was removed by blog owner at Whole New Mom)

            One study that I found interesting was this one, that found in the long run, the more diversity, the better one is able to deal with histamine.

            And the other day I found this huge study, which suggests that healthy controls have a higher diversity of bacteria, and twice as much from the Bacteroides family, compared to histamine intolerant patients.

            http://jpp.krakow.pl/journal/archive/08_18/pdf/10.26402/jpp.2018.4.09.pdf

            1. Thanks for this. Very confusing. Did you find out which of her sources was the one where the gasseri was implicated? There are so many there and I'm up to my eyeballs here. Thanks!

              BTW, the scoop can definitely be too much at first. Many people start with just a little on the tip of their finger, so that likely could have been your problem.

            2. Hi there.

              Interesting and complicated and of course not definitive. I would have to see the study. Do you know which one of her sources is the one in which gasseri is implicated?

              As for GutPro, yes that definitely could have been the issue b/c taking the scoop to start can be way too much. Some people start w/ just a little on the tip of their finger.

              As for the latter study, are they saying that you want diversity of all kinds of good bacteria?

          4. Yes, I'm not sure which study she's linking to as there are several from the same year listed in her references. You might want to contact her for clarification.

            The latter study, yes, I think -- emphasize 'think' -- that in general, that's what they're saying. I doubt though that they mean to just throw everything in at once. But gradually as one's histamine intolerance improves, then increasing diversity should make things better all around.

            One more thing. I found by accident that it seems like a lot of folks are finding benefit from using Ancestral Supplements 'Kidney' Glandular, apparently because the kidney has the highest concentration of the DAO enzyme that also helps break down histamine in the gut.

            I haven't tried it yet -- need to win the lotto -- but a google search will turn up glowing reviews on Amazon.

            1. I wish I could dive into this but I am just so swamped here. I think she needs to clarify. It's very hard to follow up on sources when an author lists them in this manner. We are supposed to trust them or spend a bunch of time trying to read their sources, not knowing which goes to what statement.

              As for the Ancestral Supplements, I have that. I tried it once but seemed to react badly to it, which might mean I need it. It's an interesting thing.

              So many other things you can try as well like homeopathy and just plain eating fewer histamine causing foods. There are other triggers as well--like mold exposure.

          5. "GutPro bacteria are very hardy and can withstand lower PH ranges than most think."

            If that's the case, why do other brands use delayed-release capsules and tablets?

            I think it's extremely unlikely that GutPro will survive as well as a capsule or tablet.

            Some of the bacteria may survive, but I think most of the more temperature-sensitive strains would be completely wiped out before reaching the gut.

          6. Adrienne,

            I didn't mean to imply that I was expecting you to 'dive into' anything. I hope you don't think others are demanding that as well.

            IMO, we all need to do as much of our own research and own inner work as possible, and stop looking to others -- or expecting others -- to solve our issues.

            Annabel, again just my opinion, but while certainly some bacteria don't survive, different strains do different things from the nose all the way to the 'other end'. And if bacteria didn't survive the gut, then kefir -- which by the way is horrible for histamine intolerant folks -- would have no effect on the gut.

            Some of it must, capsule or no capsule.

            Over and out. 🙂

  9. Very interesting article.
    I have been reading a book called The Gut Health Protocol. If you are not aware of it I think you would find it helping. Also check out a product called Phage Complete.
    Best Wishes!

    1. Thank you - lots to consider you know? SO many products. What did you like about this and the product?

  10. Hi! Do you have a recommendation for a low histamine probiotic for a 12 month old baby? We were given a rec that is adult strength and seems too intense for a baby!

    1. Hi there. Sorry for the delay - The Gut Pro one has an Infant formula and some people just give a lesser amount to a baby basing it off of body weight so that could be an option as well. Hope that helps!

  11. Hi,

    Thanks for the great post!

    Regarding Saccharomyces-Boulardii, you state:

    "...but it detoxifies gliotoxin..."

    I checked the source you provided but didn't see any reference to gliotoxin.

    I recently had a mycotoxin test and have high levels of gliotoxin, so this is of great interest to me.

    1. Hi there. Thanks for pointing that out. I'm not sure where that reference went. I found something else that, while not as helpful, is something to check out. Thanks for reading.

  12. Hi,
    Do you have an opinion on ProBio 5 from Plexus regarding histamine? It does not have to be refrigerated which works best for me.
    Thanks, Tammi

    1. Hi there. That is a conundrum. There are mostly lowering strains in there, but one is a possible concern. Also, ascorbic acid is from corn and can be an issue for some people w/ histamine intolerance. I am looking at another product that doesn't require refrigeration. Are you needing it to be shelf stable b/c you travel?

  13. Before this, without understanding about the histamine triggering probiotic. I purchased Dr Ohhiras probiotic. Honestly, it did have a positive effect on me. Somehow, after some time i noticed that my histamine level raises. Thats when i noticed and realised about the histamine triggering strains. Thankfully i did not stock up on the probiotic. However, it was a good probiotic. Just not for a histamine intolerance person

  14. Just found your blog. I have purchased a probiotic from iherb. What do you think of LactoBif Probiotics, 30 Billion CFU by california gold for histamine intolerance people? Can you check for me? And give me your opinion on it?

    1. Hi there and welcome. Casei is a histamine raising strain. That would be my concern. Thanks for reading and hope that helps!

    1. Hi there -- I have read that they might reduce histamine but I haven't researched it enough to make any statements about it.

  15. Hello ... I am in the throes of sorting out my recently diagnosed histamine intolerance. In doing research on advisable strains of probiotics I’ve encountered recommendations for Saccharomyces Boulardi. Considering this is a probiotic yeast, and yeast contributes to histamine, how is it that this particular form of yeast is copacetic with histamine intolerance, or is it?

    Thank you - every day is a challenge and learning opportunity!

    1. Hi there. Thanks for reading. I just updated the post w/ more information that should help. It's an interesting thing for sure. Let me know what you think.

  16. Yes hello my fiance has been suffering from terrible eczema and I have been trying to cure her by making home-made sauerkraut and feeding her Kefir But it has just been making it worse we have only just discovered what a histamine intolerance is and now I am wondering if there is anything I can make her which is natural and not a supplement which will help with her histamine intolerance not hinder it...

    I would be eternally grateful for any help you could give thank you so much

  17. Hi this was very informative I have a question though which natural probiotics help with a histamine intolerance?

    Please help us

  18. Hello, thanks for the excellent research.
    I came here because of the L. Casei that is in my yogurt that I consume daily. I always have allergies (was allergic to cats and dust from growing up), but just more recently I seem to have them no matter what. I had taken ciprofloxacin 2 years ago. About a week after I had a stomach virus. I had it tested and it showed up as C. Diff and H pylori. I was suppose to take another 2 rounds of antibiotics and ppi. I didnt. I had every test done from colonoscopy to MRI to stress test to ultrasounds to nerve conductive testing. All passed. But ever since then I haven't been the same. Anxiety, depression, heart racing, panic attacks, digestive issues etc. Well like you I went researching and read about gut flora. So I started consuming more yogurt and prebiotics. Limiting carbs and sugars. Also read that apple stew helps feed good bacteria. Now I read that apples are high in fructose and feed bad bacteria. I guess my question is, everything seems to change and everyone seems to have different opinions. How do we know what is correct? Are apples good or bad? Is consuming plain yogurt good or bad? There's always answers that conflict each other. How do we starve the bad bacteria and start fresh? Sorry for the rant.

    1. Hi there--I know it's really confusing. I just starting listening to something about prebiotics and the gut. Hope to learn more about this. It's hard to know what is right but one thing I do know and that is that many things depend on the person. And that avoiding pesticides and toxins is a good thing. So is drinking enough water and having good gut health and taking care of yourself.

      I am sure you have heard about the toxicity of Cipro? If not, please do read up on it. I have friends who are working on healing from it--I think they were talking about fluoride detox? It can be a really nasty drug. You might want to join our Facebook group--you could ask about it in there if you like. I think some in there have experience with it. https://www.facebook.com/groups/171490083677560/

  19. Hi!

    What do u think about the probiotic mega spore? I can’t find any of the strains it has on any of your lists 🙁
    I would order guy pro but they don’t ship to Canada. Booo.
    Thank u so much for this article as I have been searching for so long for a probiotic that didn’t bother my histamine.
    Do u think if one heals their gut that the histamine problem would be lessened?

    1. Hi there. Thanks for reading. I just went through the ingredient list. One of the strains looks to be a histamine raising strain. Another is complicated as it's in the post already (coagulans) but it was the strain that was confusing. I did find some other places on the internet talking about both Megapore and the Thrive probiotic as products to be avoided due to their raising of histamine issues so sounds like it wouldn't be a good idea based on all of this. Hope that helps.

      I don't know all that is involved with reducing histamine responses but seems to be that many things can help and gut health is important for so many things. Best wishes and hope to see you around again. There are other products on the list that do ship to Canada and I hope to add another one soon. I just went back and added in a Purium one that is another option as well.